| MD | Players | Club | Nationality | DOB | A(D) |
|---|---|---|---|---|---|
| 21-May-2022 |  Richard Wigglesworth | Leicester Tigers | England | 09-Jun-1983 | 38(347) |
| 04-Jun-2022 |  Jimmy Gopperth | London Wasps | New Zealand | 29-Jun-1983 | 38(341) |
| 04-Jun-2022 |  John Afoa | Bristol Bears | New Zealand | 16-Oct-1983 | 38(232) |
| 21-May-2022 |  Agustin Creevy | London Irish | Argentina | 15-Mar-1985 | 37(67) |
| 12-Mar-2022 |  Mike Brown | Newcastle Falcons | England | 04-Sep-1985 | 36(189) |
| 04-Jun-2022 |  Api Ratuniyarawa | Northampton Saints | Fiji | 11-Jul-1986 | 35(329) |
| 04-Jun-2022 |  Danny Care | Harlequins | England | 02-Jan-1987 | 35(154) |
| 04-Jun-2022 |  Tim Swinson | Saracens | Scotland | 11-Feb-1987 | 35(114) |
| 12-Mar-2022 |  Willi Heinz | Worcester Warriors | England | 24-Nov-1986 | 35(109) |
| 11-Feb-2022 | Tom Wood | Northampton Saints | England | 03-Nov-1986 | 35(101) |
| 21-May-2022 | Sean O'Brien | London Irish | Ireland | 14-Feb-1987 | 35(97) |
| 04-Jun-2022 | Chris Ashton | Leicester Tigers | England | 29-Mar-1987 | 35(68) |
| 20-May-2022 | David Attwood | Bristol Bears | England | 05-Apr-1987 | 35(46) |
| 04-Jun-2022 | Dan Cole | Leicester Tigers | England | 09-May-1987 | 35(27) |
| 04-Jun-2022 |  Ian Whitten | Exeter Chiefs | Ireland | 05-Jun-1987 | 34(365) |
| 04-Jun-2022 |  Kirill Gotovtsev | Gloucester | Russia | 17-Jul-1987 | 34(323) |
| 21-May-2022 |  Semesa Rokoduguni | Bath | England | 28-Aug-1987 | 34(267) |
| 19-Sep-2021 | Logoviki Mulipola | Newcastle Falcons | Samoa | 11-Mar-1987 | 34(193) |
| 04-Jun-2022 | Luther Burrell | Newcastle Falcons | England | 06-Dec-1987 | 34(181) |
| 30-Apr-2022 | Danny Cipriani | Bath | England | 02-Nov-1987 | 34(180) |
| 25-Feb-2022 | Matthew Garvey | Worcester Warriors | England | 23-Oct-1987 | 34(126) |
| 21-May-2022 | Nemani Nadolo | Leicester Tigers | Fiji | 31-Jan-1988 | 34(111) |
| 04-Jun-2022 | Alex Tait | Newcastle Falcons | England | 18-Mar-1988 | 34(78) |
| 29-Apr-2022 | Ben Stevenson | Newcastle Falcons | England | 13-Mar-1988 | 34(47) |
| 20-May-2022 | Francois Hougaard | London Wasps | South Africa | 06-Apr-1988 | 34(44) |
| 23-Apr-2022 | Will Chudley | Worcester Warriors | England | 17-Mar-1988 | 34(37) |
| 21-May-2022 | Alex Goode | Saracens | England | 07-May-1988 | 34(14) |
| 04-Jun-2022 | Alapati Leiua | Bristol Bears | Samoa | 21-Sep-1988 | 33(256) |
| 30-Apr-2022 | Sean Maitland | Saracens | Scotland | 14-Sep-1988 | 33(228) |
| 29-Jan-2022 | Ed Slater | Gloucester | England | 01-Aug-1988 | 33(181) |
| 12-Mar-2022 | Donovan Armand | Exeter Chiefs | England | 23-Sep-1988 | 33(170) |
| 26-Dec-2021 | Scott Baldwin | Worcester Warriors | Wales | 12-Jul-1988 | 33(167) |
| 21-May-2022 | Michael Young | Newcastle Falcons | England | 31-Dec-1988 | 33(141) |
| 21-May-2022 | Nick Phipps | London Irish | Australia | 09-Jan-1989 | 33(132) |
| 09-Oct-2021 | Juan Pablo Socino | Leicester Tigers | Argentina | 30-May-1988 | 33(132) |
| 12-Mar-2022 | Billy Twelvetrees | Gloucester | England | 15-Nov-1988 | 33(117) |
| 23-Oct-2021 | Joe Simpson | Bath | England | 05-Jul-1988 | 33(110) |
| 30-Jan-2022 |  William Cliff | Sale Sharks | England | 17-Oct-1988 | 33(105) |
| 04-Jun-2022 | Courtney Lawes | Northampton Saints | England | 23-Feb-1989 | 33(101) |
| 21-May-2022 | Ben Morgan | Gloucester | England | 18-Feb-1989 | 33(92) |
| 01-May-2022 | Rob Simmons | London Irish | Australia | 19-Apr-1989 | 33(12) |
| 26-Mar-2022 | Coenraad Oosthuizen | Sale Sharks | South Africa | 22-Mar-1989 | 33(4) |
| 08-Jan-2022 | Kyle Cooper | Newcastle Falcons | South Africa | 10-Feb-1989 | 32(332) |
| 19-Feb-2022 | Tom Cruse | London Wasps | England | 30-Mar-1989 | 32(326) |
| 21-May-2022 | Phillip van der Walt | Newcastle Falcons | South Africa | 14-Jul-1989 | 32(311) |
| 04-Jun-2022 | Matthew Symons | Harlequins | England | 04-Aug-1989 | 32(304) |
| 05-Mar-2022 | Kini Murimurivalu | Leicester Tigers | Fiji | 15-May-1989 | 32(294) |
| 30-Jan-2022 | Byron McGuigan | Sale Sharks | Scotland | 20-Apr-1989 | 32(285) |
| 04-Jun-2022 | Ben Youngs | Leicester Tigers | England | 05-Sep-1989 | 32(272) |
| 04-Jun-2022 | Duncan Taylor | Saracens | Scotland | 05-Sep-1989 | 32(272) |
MD = Match date,
DOB = Date of birth,
A(D) = Age(days).