| MD | Players | Club | Nationality | DOB | A(D) |
|---|---|---|---|---|---|
| 26-Feb-2022 |  Alessandro Izekor | Benetton Treviso | Italy | 05-Mar-2003 | 18(359) |
| 02-Oct-2021 | Tommaso Menoncello | Benetton Treviso | Italy | 20-Aug-2002 | 19(43) |
| 29-Jan-2022 | Canan Moodie | Bulls | South Africa | 05-Nov-2002 | 19(85) |
| 25-Feb-2022 | Ruan Venter | Lions | South Africa | 29-Nov-2002 | 19(88) |
| 24-Sep-2021 | Jordan Hendrikse | Lions | South Africa | 28-Jun-2002 | 19(88) |
| 20-May-2022 |  Cam Winnett | Cardiff Blues | Wales | 07-Jan-2003 | 19(133) |
| 22-Jan-2022 | Reinhardt Ludwig | Bulls | South Africa | 27-Aug-2002 | 19(148) |
| 26-Nov-2021 | Joe Hawkins | Ospreys | Wales | 11-Jun-2002 | 19(168) |
| 28-Jan-2022 | Lorenzo Pani | Benetton Treviso | Italy | 04-Jul-2002 | 19(208) |
| 08-Oct-2021 | Leonardo Marin | Benetton Treviso | Italy | 23-Feb-2002 | 19(227) |
| 02-Oct-2021 |  Nathan Doak | Ulster | Ireland | 17-Dec-2001 | 19(289) |
| 19-Feb-2022 | Alessandro Garbisi | Benetton Treviso | Italy | 01-Apr-2002 | 19(324) |
| 09-Oct-2021 |  Jamie Osborne | Leinster | Ireland | 16-Nov-2001 | 19(327) |
| 25-Sep-2021 | Riccardo Favretto | Benetton Treviso | Italy | 18-Oct-2001 | 19(342) |
| 28-Jan-2022 | Filippo Drago | Benetton Treviso | Italy | 24-Dec-2001 | 20(35) |
| 28-Jan-2022 | Matteo Meggiato | Benetton Treviso | Italy | 10-Dec-2001 | 20(49) |
| 20-May-2022 | Mason Grady | Cardiff Blues | Wales | 29-Mar-2002 | 20(52) |
| 29-Jan-2022 | Cathal Forde | Connacht | Ireland | 04-Nov-2001 | 20(86) |
| 11-Feb-2022 |  Ben Muncaster | Edinburgh Rugby | Scotland | 14-Oct-2001 | 20(120) |
| 28-Jan-2022 |  Carwyn Tuipulotu | Scarlets | Wales | 28-Sep-2001 | 20(122) |
| 09-Oct-2021 | Jamie Dobie | Glasgow Warriors | Scotland | 07-Jun-2001 | 20(124) |
| 09-Oct-2021 | Luca Andreani | Zebre | Italy | 19-Apr-2001 | 20(173) |
| 08-May-2022 | Will Reed | Gwent Dragons | Wales | 03-Nov-2001 | 20(186) |
| 08-Jan-2022 | Ben Moxham | Ulster | Ireland | 09-Jun-2001 | 20(213) |
| 29-Jan-2022 | Harri Deaves | Ospreys | Wales | 13-Jun-2001 | 20(230) |
| 25-Feb-2022 | Quan Horn | Lions | South Africa | 27-Jun-2001 | 20(243) |
| 26-Sep-2021 | Ben Carter | Gwent Dragons | Wales | 23-Jan-2001 | 20(246) |
| 09-Oct-2021 | Ion Neculai | Zebre | Italy | 25-Jan-2001 | 20(257) |
| 01-Oct-2021 | Sam Costelow | Scarlets | Wales | 10-Jan-2001 | 20(264) |
| 23-Apr-2022 | Chris Cosgrave | Leinster | Ireland | 24-Jul-2001 | 20(273) |
| 19-Mar-2022 | Simone Gesi | Zebre | Italy | 23-May-2001 | 20(300) |
| 01-Jan-2022 |  Alex Kendellen | Munster | Ireland | 03-Mar-2001 | 20(304) |
| 29-Jan-2022 | Joe McCarthy | Leinster | Ireland | 26-Mar-2001 | 20(309) |
| 15-Oct-2021 | Sibusio Sangweni | Lions | South Africa | 27-Nov-2000 | 20(322) |
| 26-Feb-2022 | Nicola Piantella | Benetton Treviso | Italy | 28-Mar-2001 | 20(335) |
| 26-Sep-2021 | Aneurin Owen | Gwent Dragons | Wales | 19-Oct-2000 | 20(342) |
| 25-Sep-2021 | Gianmarco Lucchesi | Benetton Treviso | Italy | 10-Sep-2000 | 21(15) |
| 23-Apr-2022 | Harry Fry | Gwent Dragons | England | 05-Apr-2001 | 21(18) |
| 19-Feb-2022 | Lorenzo Cannone | Benetton Treviso | Italy | 28-Jan-2001 | 21(22) |
| 09-Oct-2021 | Andrea Zambonin | Zebre | Italy | 03-Sep-2000 | 21(36) |
| 24-Sep-2021 | Ethan McIlroy | Ulster | Ireland | 10-Aug-2000 | 21(45) |
| 01-Oct-2021 | Jac Price | Scarlets | Wales | 04-Aug-2000 | 21(58) |
| 01-Jan-2022 | Harri O'Connor | Scarlets | Wales | 25-Oct-2000 | 21(68) |
| 30-Apr-2022 | Alex Soroka | Leinster | Ireland | 19-Feb-2001 | 21(70) |
| 24-Sep-2021 | Emmanuel Tshituka | Lions | South Africa | 16-Jun-2000 | 21(100) |
| 02-Oct-2021 | David McCann | Ulster | Ireland | 13-Jun-2000 | 21(111) |
| 11-Feb-2022 | Martin Moloney | Leinster | Ireland | 19-Oct-2000 | 21(115) |
| 03-Dec-2021 | Richard Kriel | Bulls | South Africa | 07-Jul-2000 | 21(149) |
| 25-Sep-2021 | Manuel Zuliani | Benetton Treviso | Italy | 26-Apr-2000 | 21(152) |
| 29-Jan-2022 | Oli Smith | Glasgow Warriors | Scotland | 07-Aug-2000 | 21(175) |
MD = Match date,
DOB = Date of birth,
A(D) = Age(days).