| A(D) | Club | VS | MD | |
|---|---|---|---|---|
| 21(131) | Bulls | Western Stormers | 22-Jan-2022 | Match Details |
| 22(180) | Edinburgh Rugby | Ospreys | 29-Jan-2022 | Match Details |
| 23(343) | Benetton Treviso | Glasgow Warriors | 19-Feb-2022 | Match Details |
| 24(56) | Zebre | Western Stormers | 13-Mar-2022 | Match Details |
| 24(185) | Leinster | Sharks | 23-Apr-2022 | Match Details |
| 25(227) | Gwent Dragons | Zebre | 30-Apr-2022 | Match Details |
| 25(317) | Lions | Ulster | 15-Oct-2021 | Match Details |
| 25(363) | Munster | Zebre | 29-Jan-2022 | Match Details |
| 25(21) | Sharks | Cardiff Blues | 16-Oct-2021 | Match Details |
| 26(364) | Connacht | Munster | 16-Oct-2021 | Match Details |
| 26(159) | Ulster | Ospreys | 04-Dec-2021 | Match Details |
| 26(166) | Ospreys | Edinburgh Rugby | 29-Jan-2022 | Match Details |
| 27(216) | Scarlets | Ulster | 28-Jan-2022 | Match Details |
| 27(338) | Western Stormers | Ospreys | 02-Apr-2022 | Match Details |
| 27(353) | Glasgow Warriors | Ospreys | 08-Jan-2022 | Match Details |
| 27(26) | Cardiff Blues | Munster | 29-Apr-2022 | Match Details |
MD = Match date,
A(D) = Age(days).