| Points | Club | VS Club | Date | |
|---|---|---|---|---|
| 69 | Benetton Treviso | Cardiff Blues | 20-05-2022 | Match details |
| 64 | Munster | Gwent Dragons | 05-03-2022 | Match details |
| 61 | Leinster | Benetton Treviso | 05-03-2022 | Match details |
| 57 | Bulls | Scarlets | 18-03-2022 | Match details |
| 56 | Edinburgh Rugby | Connacht | 04-03-2022 | Match details |
| 55 | Western Stormers | Zebre | 13-03-2022 | Match details |
| 54 | Ospreys | Scarlets | 30-04-2022 | Match details |
| 51 | Sharks | Gwent Dragons | 01-04-2022 | Match details |
| 49 | Scarlets | Cardiff Blues | 09-04-2022 | Match details |
| 48 | Ulster | Cardiff Blues | 04-03-2022 | Match details |
| 46 | Connacht | Ospreys | 26-11-2021 | Match details |
| 45 | Lions | Ospreys | 25-03-2022 | Match details |
| 42 | Cardiff Blues | Zebre | 06-05-2022 | Match details |
| 42 | Glasgow Warriors | Connacht | 29-01-2022 | Match details |
| 38 | Gwent Dragons | Scarlets | 16-04-2022 | Match details |
| 26 | Zebre | Edinburgh Rugby | 22-04-2022 | Match details |
