| A(D) | Club | VS | MD | |
|---|---|---|---|---|
| 26(258) | Newcastle Falcons | Sale Sharks | 19-Nov-2021 | Match Details |
| 25(170) | Leicester Tigers | London Wasps | 20-Nov-2021 | Match Details |
| 25(228) | Gloucester | Exeter Chiefs | 20-Nov-2021 | Match Details |
| 23(140) | Exeter Chiefs | Gloucester | 20-Nov-2021 | Match Details |
| 23(89) | Saracens | London Irish | 19-Nov-2021 | Match Details |
| 23(68) | Bristol Bears | Worcester Warriors | 20-Nov-2021 | Match Details |
| 23(229) | Northampton Saints | Harlequins | 19-Nov-2021 | Match Details |
| 21(332) | Harlequins | Northampton Saints | 19-Nov-2021 | Match Details |
| 21(256) | London Irish | Saracens | 19-Nov-2021 | Match Details |
| 20(364) | Worcester Warriors | Bristol Bears | 20-Nov-2021 | Match Details |
| 20(190) | Sale Sharks | Newcastle Falcons | 19-Nov-2021 | Match Details |
| 18(10) | London Wasps | Leicester Tigers | 20-Nov-2021 | Match Details |
MD = Match date,
A(D) = Age(days).