| MD | Players | Nationality | DOB | A(D) |
|---|---|---|---|---|
| 19-Mar-2022 | Jonathan Sexton | Ireland | 11-Jul-1985 | 36(251) |
| 19-Mar-2022 | Cian Healy | Ireland | 07-Oct-1987 | 34(164) |
| 12-Mar-2022 | Peter O'Mahony | Ireland | 17-Sep-1989 | 32(176) |
| 19-Mar-2022 | Bundee Aki | Ireland | 07-Apr-1990 | 31(347) |
| 12-Mar-2022 | Andrew Conway | Ireland | 11-Jul-1991 | 30(245) |
| 19-Mar-2022 | Iain Henderson | Ireland | 21-Feb-1992 | 30(27) |
| 19-Mar-2022 | Jamieson Gibson-Park | Ireland | 10-May-1992 | 29(313) |
| 19-Mar-2022 | James Lowe | Wales | 08-Jul-1992 | 29(254) |
| 19-Mar-2022 | Jack Conan | Ireland | 29-Jul-1992 | 29(233) |
| 19-Mar-2022 | Tadhg Beirne | Ireland | 01-Aug-1992 | 29(230) |
| 19-Mar-2022 | Tadhg Furlong | Ireland | 14-Nov-1992 | 29(125) |
| 19-Mar-2022 | Josh van der Flier | Ireland | 25-Apr-1993 | 28(328) |
| 27-Feb-2022 | Robbie Henshaw | Ireland | 12-Jun-1993 | 28(260) |
| 19-Mar-2022 | Gary Ringrose | Ireland | 26-Jan-1995 | 27(52) |
| 27-Feb-2022 | Joey Carbery | Ireland | 01-Nov-1995 | 26(119) |
| 27-Feb-2022 | Andrew Porter | Ireland | 16-Jan-1996 | 26(43) |
| 19-Mar-2022 | Hugo Keenan | Ireland | 18-Jun-1996 | 25(274) |
| 12-Mar-2022 | James Ryan | Ireland | 24-Jul-1996 | 25(231) |
| 12-Feb-2022 | Ronan Kelleher | Ireland | 24-Jan-1998 | 24(19) |
| 19-Mar-2022 | Mackenzie Hansen | Ireland | 27-Mar-1998 | 23(357) |
| 19-Mar-2022 | Caelan Doris | Ireland | 02-Apr-1998 | 23(351) |
| 27-Feb-2022 | Michael Lowry | Ireland | 20-Aug-1998 | 23(191) |
| 19-Mar-2022 | Dan Sheehan | Ireland | 17-Sep-1998 | 23(183) |
| 27-Feb-2022 | Ryan Baird | Ireland | 26-Jul-1999 | 22(217) |
MD = Match date,
DOB = Date of birth,
A(D) = Age(days).