| Points | Players | VS Club | Date | |
|---|---|---|---|---|
| 19 | John Cooney | Clermont Auvergne | 11-12-2021 | Match details |
| 15 | Robert Baloucoune | Toulouse | 09-04-2022 | Match details |
| 10 | Michael Lowry | Northampton Saints | 16-01-2022 | Match details |
| 10 | Robert Herring | Clermont Auvergne | 22-01-2022 | Match details |
| 9 | Nathan Doak | Northampton Saints | 16-01-2022 | Match details |
| 7 | Nathan Doak | Clermont Auvergne | 22-01-2022 | Match details |
| 6 | John Cooney | Toulouse | 09-04-2022 | Match details |
| 5 | Stuart McCloskey | Clermont Auvergne | 11-12-2021 | Match details |
| 5 | Nick Timoney | Clermont Auvergne | 11-12-2021 | Match details |
| 5 | Robert Baloucoune | Northampton Saints | 16-01-2022 | Match details |
| 5 | Michael Lowry | Clermont Auvergne | 22-01-2022 | Match details |
| 5 | Duane Vermeulan | Clermont Auvergne | 22-01-2022 | Match details |
| 5 | Robert Baloucoune | Clermont Auvergne | 22-01-2022 | Match details |
| 5 | Andrew Warwick | Toulouse | 09-04-2022 | Match details |
| 2 | Billy Burns | Clermont Auvergne | 22-01-2022 | Match details |
