| Points | Players | VS Club | Date | |
|---|---|---|---|---|
| 20 | Gavin Coombes | Zebre | 11-06-2021 | Match details |
| 13 | JJ Hanrahan | Ulster | 07-05-2021 | Match details |
| 12 | Joey Carbery | Zebre | 11-06-2021 | Match details |
| 10 | Conor Murray | Leinster | 24-04-2021 | Match details |
| 10 | Joey Carbery | Leinster | 24-04-2021 | Match details |
| 10 | Rory Scannell | Ulster | 07-05-2021 | Match details |
| 10 | Craig Casey | Zebre | 11-06-2021 | Match details |
| 5 | Conor Murray | Ulster | 07-05-2021 | Match details |
| 5 | Michael Haley | Ulster | 07-05-2021 | Match details |
| 5 | Andrew Conway | Ulster | 07-05-2021 | Match details |
| 5 | Niall Scannell | Zebre | 11-06-2021 | Match details |
| 5 | Liam Coombes | Zebre | 11-06-2021 | Match details |
| 2 | Jake Flannery | Zebre | 11-06-2021 | Match details |
