| Points | Players | VS Club | Date | |
|---|---|---|---|---|
| 17 | Leigh Halfpenny | Ospreys | 08-05-2021 | Match details |
| 10 | Steffan Evans | Gwent Dragons | 25-04-2021 | Match details |
| 10 | Kieran Hardy | Edinburgh Rugby | 13-06-2021 | Match details |
| 7 | Sam Costelow | Gwent Dragons | 25-04-2021 | Match details |
| 5 | Iestyn Rees | Gwent Dragons | 25-04-2021 | Match details |
| 5 | Dane Blacker | Gwent Dragons | 25-04-2021 | Match details |
| 5 | Johnny McNicholl | Gwent Dragons | 25-04-2021 | Match details |
| 5 | Alex Jeffries | Ospreys | 08-05-2021 | Match details |
| 5 | Tom Rogers | Edinburgh Rugby | 13-06-2021 | Match details |
| 5 | Dafydd Hughes | Edinburgh Rugby | 13-06-2021 | Match details |
| 4 | Daniel Jones | Edinburgh Rugby | 13-06-2021 | Match details |
| 4 | Sam Costelow | Edinburgh Rugby | 13-06-2021 | Match details |
