| Penalties | Players | Club | VS Club | Date | |
|---|---|---|---|---|---|
| 3 |  Francisco Urroz | Selknam | Jaguares XV | 20-05-2022 | Match details |
| 3 | Felipe Etcheverry Cavanna | Penarol | Selknam | 27-05-2022 | Match details |
| 2 | Eliseo Morales | Cafeteros Pro | Penarol | 21-05-2022 | Match details |
| 2 | Francisco Urroz | Selknam | Penarol | 27-05-2022 | Match details |
| 1 | Geronimo Priscantelli | Jaguares XV | Selknam | 20-05-2022 | Match details |
| 1 | Felipe Etcheverry Cavanna | Penarol | Cafeteros Pro | 21-05-2022 | Match details |
