| Penalties | Players | VS Club | Date | |
|---|---|---|---|---|
| 4 | Diego Walter | Selknam | 13-03-2022 | Match details |
| 3 | Diego Walter | Penarol | 27-03-2022 | Match details |
| 3 | Sebastian Urbieta | Penarol | 04-05-2022 | Match details |
| 2 | Sebastian Urbieta | Penarol | 27-03-2022 | Match details |
| 2 | Sebastian Urbieta | Corinthians | 02-04-2022 | Match details |
| 1 | Diego Walter | Jaguares XV | 19-03-2022 | Match details |
| 1 | Sebastian Urbieta | Corinthians | 10-05-2022 | Match details |
| 1 | Diego Walter | Cafeteros Pro | 15-05-2022 | Match details |
