| Penalties | Players | VS Club | Date | |
|---|---|---|---|---|
| 5 | Santiago Videla | Penarol | 26-04-2021 | Match details |
| 4 | Patricio Baronio-Gauna | Olimpia Lions | 21-03-2021 | Match details |
| 2 | Santiago Videla | Corinthians | 01-05-2021 | Match details |
| 1 | Santiago Videla | Cafeteros Pro | 16-03-2021 | Match details |
| 1 | Santiago Videla | Jaguares XV | 25-03-2021 | Match details |
| 1 | Patricio Baronio-Gauna | Penarol | 30-03-2021 | Match details |
| 1 | Patricio Baronio-Gauna | Jaguares XV | 21-04-2021 | Match details |
