| MD | Players | Club | Nationality | DOB | A(D) |
|---|---|---|---|---|---|
| 18-Dec-2021 |  Cam Winnett | Cardiff Blues | Wales | 07-Jan-2003 | 18(346) |
| 15-Jan-2022 |  Leo Barre | Stade Francais | France | 20-Aug-2002 | 19(148) |
| 16-Jan-2022 |  Axel Bevia | Montpellier | France | 14-May-2002 | 19(247) |
| 16-Jan-2022 |  Tom Litchfield | Northampton Saints | England | 20-Apr-2002 | 19(271) |
| 15-Jan-2022 | Ewan Richards | Bath | England | 05-Apr-2002 | 19(285) |
| 11-Dec-2021 | Louis Foursans-Bourdette | Montpellier | France | 29-Jan-2002 | 19(316) |
| 09-Apr-2022 | Nolann Le Garrec | Racing CF | France | 14-May-2002 | 19(330) |
| 16-Dec-2021 |  Jamie Osborne | Leinster | Ireland | 16-Nov-2001 | 20(30) |
| 16-Jan-2022 |  Nathan Doak | Ulster | Ireland | 17-Dec-2001 | 20(30) |
| 11-Dec-2021 | Orlando Bailey | Bath | England | 29-Sep-2001 | 20(73) |
| 15-Jan-2022 |  Charlie Atkinson | London Wasps | England | 07-Oct-2001 | 20(100) |
| 16-Jan-2022 |  Daniel Bibi Biziwu | Clermont Auvergne | France | 29-Aug-2001 | 20(140) |
| 23-Jan-2022 |  Rafi Quirke | Sale Sharks | England | 18-Aug-2001 | 20(158) |
| 11-Dec-2021 |  George Martin | Leicester Tigers | England | 18-Jun-2001 | 20(176) |
| 19-Dec-2021 | Daniel Kelly | Leicester Tigers | England | 16-Jun-2001 | 20(186) |
| 11-Dec-2021 | Jack van Poortvliet | Leicester Tigers | England | 15-May-2001 | 20(210) |
| 23-Jan-2022 | Harri Deaves | Ospreys | Wales | 13-Jun-2001 | 20(224) |
| 11-Dec-2021 | Jacob Beetham | Cardiff Blues | Wales | 18-Apr-2001 | 20(237) |
| 10-Dec-2021 | Thomas Freeman | Northampton Saints | England | 05-Mar-2001 | 20(280) |
| 15-Jan-2022 |  Ioan Lloyd | Bristol Bears | Wales | 05-Apr-2001 | 20(285) |
| 09-Apr-2022 | Ben Moxham | Ulster | Ireland | 09-Jun-2001 | 20(304) |
| 09-Apr-2022 | Jack Bates | Bristol Bears | England | 26-May-2001 | 20(318) |
| 16-Jan-2022 |  Sam Costelow | Scarlets | Wales | 10-Jan-2001 | 21(6) |
| 15-Jan-2022 | Anthime Hemery | Racing CF | France | 09-Jan-2001 | 21(6) |
| 16-Jan-2022 | Tom Roebuck | Sale Sharks | England | 07-Jan-2001 | 21(9) |
| 19-Dec-2021 | Freddie Steward | Leicester Tigers | England | 05-Dec-2000 | 21(14) |
| 11-Dec-2021 | Kevin Viallard | Clermont Auvergne | France | 27-Nov-2000 | 21(14) |
| 09-Apr-2022 | Max Spring | Racing CF | France | 15-Mar-2001 | 21(25) |
| 09-Apr-2022 |  Alex Kendellen | Munster | Ireland | 03-Mar-2001 | 21(37) |
| 11-Dec-2021 | Tani Vili | Clermont Auvergne | France | 31-Oct-2000 | 21(41) |
| 14-Jan-2022 |  Louis Lynagh | Harlequins | England | 03-Dec-2000 | 21(42) |
| 11-Dec-2021 | Federico Mori | Begles-Bordeaux | Italy | 13-Oct-2000 | 21(59) |
| 23-Jan-2022 | Emmanuel Iyogun | Northampton Saints | England | 24-Nov-2000 | 21(60) |
| 22-Jan-2022 | Gabriel Hamer-Webb | Bath | England | 07-Nov-2000 | 21(76) |
| 28-May-2022 | Matthias Haddad | La Rochelle | France | 10-Mar-2001 | 21(79) |
| 11-Dec-2021 | Max Ojomoh | Bath | England | 13-Sep-2000 | 21(89) |
| 16-Jan-2022 | Tyler Duguid | Montpellier | Canada | 17-Oct-2000 | 21(91) |
| 11-Dec-2021 | Oliver Chessum | Leicester Tigers | England | 06-Sep-2000 | 21(96) |
| 15-Jan-2022 | Alfie Barbeary | London Wasps | England | 05-Oct-2000 | 21(102) |
| 11-Dec-2021 | Ethan McIlroy | Ulster | Ireland | 10-Aug-2000 | 21(123) |
| 16-Jan-2022 | Bevan Rodd | Sale Sharks | England | 26-Aug-2000 | 21(143) |
| 11-Dec-2021 | Yoram Moefana | Begles-Bordeaux | France | 18-Jul-2000 | 21(146) |
| 16-Jan-2022 | Thibault Lanen | Clermont Auvergne | France | 01-Aug-2000 | 21(168) |
| 21-Jan-2022 | Florent van Verberghe | Castres | France | 22-Jul-2000 | 21(183) |
| 23-Jan-2022 | Josh Thomas | Ospreys | Wales | 30-Jun-2000 | 21(207) |
| 16-Jan-2022 | Nathanael Hulleu | Begles-Bordeaux | France | 16-May-2000 | 21(245) |
| 10-Apr-2022 | George Hammond | Harlequins | England | 31-Jul-2000 | 21(253) |
| 18-Dec-2021 | Hugh Tizard | Harlequins | England | 31-Mar-2000 | 21(262) |
| 18-Dec-2021 | Simon Meka | Castres | France | 14-Mar-2000 | 21(279) |
| 23-Jan-2022 | Ollie Sleightholme | Northampton Saints | England | 13-Apr-2000 | 21(285) |
MD = Match date,
DOB = Date of birth,
A(D) = Age(days).