| MD | Players | Nationality | DOB | A(D) |
|---|---|---|---|---|
| 05-Feb-2022 | Freddie Steward | England | 05-Dec-2000 | 21(62) |
| 05-Feb-2022 | Marcus Smith | England | 14-Feb-1999 | 22(357) |
| 05-Feb-2022 | Tom Curry | England | 15-Jun-1998 | 23(235) |
| 05-Feb-2022 | Nicholas Isiekwe | England | 20-Apr-1998 | 23(291) |
| 13-Feb-2022 | Harry Randall | England | 18-Dec-1997 | 24(57) |
| 13-Feb-2022 | Alex Dombrandt | England | 15-May-1997 | 24(274) |
| 05-Feb-2022 | Max Malins | England | 07-Jan-1997 | 25(29) |
| 19-Mar-2022 | George Furbank | England | 17-Oct-1996 | 25(153) |
| 05-Feb-2022 | Joe Marchant | England | 16-Jul-1996 | 25(204) |
| 13-Feb-2022 | William Stuart | England | 12-Jul-1996 | 25(216) |
| 19-Mar-2022 | Sam Underhill | England | 22-Jul-1996 | 25(240) |
| 13-Feb-2022 | Charlie Ewels | England | 29-Jun-1995 | 26(230) |
| 05-Feb-2022 | Ellis Genge | England | 16-Feb-1995 | 26(355) |
| 05-Feb-2022 | Sam Simmonds | England | 10-Nov-1994 | 27(87) |
| 05-Feb-2022 | Maro Itoje | England | 28-Oct-1994 | 27(100) |
| 05-Feb-2022 | Lewis Ludlow | England | 11-Sep-1994 | 27(147) |
| 05-Feb-2022 | Luke Cowan-Dickie | England | 20-Jun-1993 | 28(230) |
| 13-Feb-2022 | Jack Nowell | England | 11-Apr-1993 | 28(308) |
| 05-Feb-2022 | Kyle Sinckler | England | 30-Mar-1993 | 28(312) |
| 05-Feb-2022 | Henry Slade | England | 19-Mar-1993 | 28(323) |
| 05-Feb-2022 | Elliot Daly | England | 08-Oct-1992 | 29(120) |
| 13-Feb-2022 | Jamie George | England | 20-Oct-1990 | 31(117) |
| 05-Feb-2022 | Ben Youngs | England | 05-Sep-1989 | 32(153) |
| 26-Feb-2022 | Courtney Lawes | England | 23-Feb-1989 | 33(3) |
MD = Match date,
DOB = Date of birth,
A(D) = Age(days).