| MD | Players | Club | Nationality | DOB | A(D) |
|---|---|---|---|---|---|
| 18-Jun-2022 |  Richard Wigglesworth | Leicester Tigers | England | 09-Jun-1983 | 39(10) |
| 11-Jun-2022 |  Api Ratuniyarawa | Northampton Saints | Fiji | 11-Jul-1986 | 35(336) |
| 11-Jun-2022 |  Danny Care | Harlequins | England | 02-Jan-1987 | 35(161) |
| 11-Jun-2022 |  Tim Swinson | Saracens | Scotland | 11-Feb-1987 | 35(121) |
| 18-Jun-2022 | Chris Ashton | Leicester Tigers | England | 29-Mar-1987 | 35(82) |
| 18-Jun-2022 | Dan Cole | Leicester Tigers | England | 09-May-1987 | 35(41) |
| 18-Jun-2022 | Alex Goode | Saracens | England | 07-May-1988 | 34(42) |
| 18-Jun-2022 | Sean Maitland | Saracens | Scotland | 14-Sep-1988 | 33(277) |
| 11-Jun-2022 | Courtney Lawes | Northampton Saints | England | 23-Feb-1989 | 33(108) |
| 11-Jun-2022 | Matthew Symons | Harlequins | England | 04-Aug-1989 | 32(311) |
| 11-Jun-2022 | Ben Youngs | Leicester Tigers | England | 05-Sep-1989 | 32(279) |
| 11-Jun-2022 | Daniel Biggar | Northampton Saints | Wales | 16-Oct-1989 | 32(238) |
| 18-Jun-2022 | Vincent Koch | Saracens | South Africa | 13-Mar-1990 | 32(97) |
| 11-Jun-2022 | Joe Marler | Harlequins | England | 07-Jul-1990 | 31(339) |
| 18-Jun-2022 | Callum Green | Leicester Tigers | England | 15-Jul-1990 | 31(339) |
| 18-Jun-2022 | Jamie George | Saracens | England | 20-Oct-1990 | 31(241) |
| 18-Jun-2022 | Makovina Vunipola | Saracens | England | 13-Jan-1991 | 31(157) |
| 18-Jun-2022 | Matias Moroni | Leicester Tigers | Argentina | 29-Mar-1991 | 31(81) |
| 11-Jun-2022 | Will Collier | Harlequins | England | 05-May-1991 | 31(38) |
| 11-Jun-2022 | Courtnall Skosan | Northampton Saints | South Africa | 24-Jul-1991 | 30(323) |
| 18-Jun-2022 | Owen Farrell | Saracens | England | 21-Sep-1991 | 30(271) |
| 11-Jun-2022 | Sam Matavesi | Northampton Saints | Fiji | 13-Jan-1992 | 30(150) |
| 11-Jun-2022 | Stephan Lewies | Harlequins | South Africa | 27-Jan-1992 | 30(136) |
| 18-Jun-2022 | Aled Davies | Saracens | Wales | 19-Jul-1992 | 29(334) |
| 18-Jun-2022 | Elliot Daly | Saracens | England | 08-Oct-1992 | 29(253) |
| 11-Jun-2022 | Matt Proctor | Northampton Saints | New Zealand | 26-Oct-1992 | 29(228) |
| 18-Jun-2022 | Billy Vunipola | Saracens | England | 03-Nov-1992 | 29(227) |
| 18-Jun-2022 | George Ford | Leicester Tigers | England | 16-Mar-1993 | 29(94) |
| 11-Jun-2022 | Harry Wells | Leicester Tigers | England | 29-Sep-1993 | 28(255) |
| 18-Jun-2022 | Julian Montoya | Leicester Tigers | Argentina | 29-Oct-1993 | 28(232) |
| 11-Jun-2022 | Huw Jones | Harlequins | Scotland | 17-Dec-1993 | 28(176) |
| 11-Jun-2022 | Andre Esterhuizen | Harlequins | South Africa | 30-Mar-1994 | 28(73) |
| 18-Jun-2022 | Maro Itoje | Saracens | England | 28-Oct-1994 | 27(233) |
| 18-Jun-2022 | Nick Tompkins | Saracens | Wales | 16-Feb-1995 | 27(122) |
| 18-Jun-2022 | Ellis Genge | Leicester Tigers | England | 16-Feb-1995 | 27(122) |
| 18-Jun-2022 | Hanro Liebenberg | Leicester Tigers | South Africa | 10-Oct-1995 | 26(252) |
| 18-Jun-2022 | Theo McFarland | Saracens | Samoa | 16-Oct-1995 | 26(246) |
| 18-Jun-2022 | Jasper Wiese | Leicester Tigers | South Africa | 21-Oct-1995 | 26(241) |
| 11-Jun-2022 | Lewis Ludlam | Northampton Saints | England | 08-Dec-1995 | 26(186) |
| 11-Jun-2022 | Rory Hutchinson | Northampton Saints | Scotland | 29-Jan-1996 | 26(134) |
| 11-Jun-2022 | Jack Walker | Harlequins | England | 06-May-1996 | 26(36) |
| 11-Jun-2022 | Joe Marchant | Harlequins | England | 16-Jul-1996 | 25(330) |
| 18-Jun-2022 | Max Malins | Saracens | England | 07-Jan-1997 | 25(162) |
| 18-Jun-2022 | Guy Porter | Leicester Tigers | England | 23-Jan-1997 | 25(146) |
| 11-Jun-2022 | William Evans | Harlequins | England | 28-Jan-1997 | 25(134) |
| 11-Jun-2022 | Alex Dombrandt | Harlequins | England | 15-May-1997 | 25(27) |
| 11-Jun-2022 | Alex Mitchell | Northampton Saints | England | 25-May-1997 | 25(17) |
| 18-Jun-2022 | Harry Potter | Leicester Tigers | England | 15-Dec-1997 | 24(185) |
| 11-Jun-2022 | Juarno Augustus | Northampton Saints | South Africa | 09-Dec-1997 | 24(184) |
| 18-Jun-2022 | Benjamin Earl | Saracens | England | 07-Jan-1998 | 24(162) |
MD = Match date,
DOB = Date of birth,
A(D) = Age(days).