| MD | Players | Club | Nationality | DOB | A(D) |
|---|---|---|---|---|---|
| 19-Jun-2021 |  Jayden Hayward | Benetton Treviso | Italy | 30-Nov-1982 | 38(202) |
| 01-May-2021 | Jannie Du Plessis | Lions | South Africa | 16-Nov-1982 | 38(167) |
| 29-May-2021 | Richard Hibbard | Gwent Dragons | Wales | 13-Dec-1983 | 37(168) |
| 05-Jun-2021 |  Josh Turnbull | Cardiff Blues | Wales | 12-Mar-1984 | 37(85) |
| 11-Jun-2021 |  Scott Fardy | Leinster | Australia | 05-Jul-1984 | 36(341) |
| 12-Jun-2021 | Morne Steyn | Bulls | South Africa | 11-Jul-1984 | 36(336) |
| 04-Jun-2021 | Stephen Myler | Ospreys | England | 21-Jul-1984 | 36(318) |
| 04-Jun-2021 | Bradley Davies | Ospreys | Wales | 09-Jan-1985 | 36(146) |
| 11-Jun-2021 | Juan Harris | Gwent Dragons | South Africa | 22-Feb-1985 | 36(109) |
| 14-May-2021 |  Billy Holland | Munster | Ireland | 03-Aug-1985 | 35(285) |
| 16-May-2021 | Alan Wyn Jones | Ospreys | Wales | 19-Sep-1985 | 35(240) |
| 07-May-2021 |  Alby Mathewson | Ulster | New Zealand | 13-Dec-1985 | 35(146) |
| 11-Jun-2021 | Michael Bent | Leinster | Ireland | 25-Apr-1986 | 35(48) |
| 05-Jun-2021 |  Willem Petrus Nel | Edinburgh Rugby | Scotland | 30-Apr-1986 | 35(37) |
| 11-Jun-2021 | Aaron Jarvis | Gwent Dragons | Wales | 20-May-1986 | 35(23) |
| 14-May-2021 | Sean Cronin | Leinster | Ireland | 06-May-1986 | 35(9) |
| 04-Jun-2021 | Duane Vermeulan | Bulls | South Africa | 03-Jul-1986 | 34(337) |
| 11-Jun-2021 | Jamie Roberts | Gwent Dragons | Wales | 08-Nov-1986 | 34(216) |
| 24-Apr-2021 | Rhys Gill | Cardiff Blues | Wales | 30-Oct-1986 | 34(177) |
| 08-May-2021 |  Ken Owens | Scarlets | Wales | 03-Jan-1987 | 34(126) |
| 25-Apr-2021 | Marc Jones | Scarlets | Wales | 03-Apr-1987 | 34(23) |
| 28-May-2021 | Tommy O'Donnell | Munster | Ireland | 21-May-1987 | 34(8) |
| 15-May-2021 | Aaron Shingler | Scarlets | Wales | 07-Aug-1987 | 33(282) |
| 11-Jun-2021 | Cian Healy | Leinster | Ireland | 07-Oct-1987 | 33(248) |
| 24-Apr-2021 | Keith Earls | Munster | Ireland | 02-Oct-1987 | 33(205) |
| 28-May-2021 | Stephen Archer | Munster | Ireland | 29-Jan-1988 | 33(120) |
| 19-Jun-2021 | Cornal Hendricks | Bulls | South Africa | 18-Apr-1988 | 33(62) |
| 15-May-2021 | Jon Davies | Scarlets | Wales | 05-Apr-1988 | 33(40) |
| 19-Jun-2021 | Dewaldt Otto Duvenage | Benetton Treviso | South Africa | 22-May-1988 | 33(28) |
| 23-Apr-2021 | Lee-Roy Atalifo | Edinburgh Rugby | Fiji | 10-May-1988 | 32(348) |
| 11-Jun-2021 | John Ryan | Munster | Ireland | 02-Aug-1988 | 32(313) |
| 07-May-2021 | Ian Nagle | Zebre | Ireland | 17-Oct-1988 | 32(202) |
| 04-Jun-2021 | Daniel Evans | Ospreys | Wales | 15-Nov-1988 | 32(201) |
| 11-Jun-2021 | Dave Kilcoyne | Munster | Ireland | 14-Dec-1988 | 32(179) |
| 04-Jun-2021 | Rhys Webb | Ospreys | Wales | 09-Dec-1988 | 32(177) |
| 19-Jun-2021 | Stravino Jacobs | Bulls | South Africa | 21-Jan-1989 | 32(149) |
| 15-May-2021 | Leigh Halfpenny | Scarlets | Wales | 22-Dec-1988 | 32(144) |
| 05-Jun-2021 | Jason Harries | Cardiff Blues | Wales | 14-Feb-1989 | 32(111) |
| 05-Jun-2021 | Ian Madigan | Ulster | Ireland | 21-Mar-1989 | 32(76) |
| 14-May-2021 | Matthew Healy | Connacht | Ireland | 14-Mar-1989 | 32(61) |
| 04-Jun-2021 | Rosco Specman | Western Stormers | South Africa | 28-Apr-1989 | 32(37) |
| 22-May-2021 | Trevor Nyakane | Bulls | South Africa | 04-May-1989 | 32(18) |
| 04-Jun-2021 | Ryan Wilson | Glasgow Warriors | Scotland | 18-May-1989 | 32(17) |
| 07-May-2021 | Conor Murray | Munster | Ireland | 20-Apr-1989 | 32(17) |
| 15-May-2021 | Alexandru Tarus | Zebre | Romania | 09-May-1989 | 32(6) |
| 14-May-2021 | Sean Reidy | Ulster | Ireland | 10-May-1989 | 32(4) |
| 24-Apr-2021 | Jason Tovey | Cardiff Blues | Wales | 28-Apr-1989 | 31(361) |
| 04-Jun-2021 | Fraser Brown | Glasgow Warriors | Scotland | 20-Jun-1989 | 31(350) |
| 13-Jun-2021 | Henry Pyrgos | Edinburgh Rugby | Scotland | 09-Jul-1989 | 31(339) |
| 16-May-2021 | Greg Bateman | Gwent Dragons | England | 20-Jun-1989 | 31(331) |
MD = Match date,
DOB = Date of birth,
A(D) = Age(days).