| Points | Players | VS Club | Date | |
|---|---|---|---|---|
| 10 | Alfie Barbeary | Montpellier | 18-12-2020 | Match details |
| 10 | Jacob Umaga | Clermont Auvergne | 03-04-2021 | Match details |
| 7 | Charlie Atkinson | Montpellier | 18-12-2020 | Match details |
| 6 | Jimmy Gopperth | Montpellier | 18-12-2020 | Match details |
| 5 | Tom Cruse | Gwent Dragons | 12-12-2020 | Match details |
| 5 | Dan Robson | Gwent Dragons | 12-12-2020 | Match details |
| 5 | Jack Willis | Gwent Dragons | 12-12-2020 | Match details |
| 5 | Thomas Young | Gwent Dragons | 12-12-2020 | Match details |
| 5 | James Gaskell | Montpellier | 18-12-2020 | Match details |
| 5 | Paolo Odogwu | Montpellier | 18-12-2020 | Match details |
| 5 | Paolo Odogwu | Clermont Auvergne | 03-04-2021 | Match details |
| 5 | Joshua Bassett | Clermont Auvergne | 03-04-2021 | Match details |
| 5 | Ben Harris | Clermont Auvergne | 03-04-2021 | Match details |
| 4 | Jimmy Gopperth | Gwent Dragons | 12-12-2020 | Match details |
