| Penalties | Players | VS Club | Date | |
|---|---|---|---|---|
| 3 | Federico Favaro | Corinthians | 13-03-2022 | Match details |
| 2 | Federico Favaro | Cafeteros Pro | 19-03-2022 | Match details |
| 2 | Nicolas Roger Farias | Olimpia Lions | 27-03-2022 | Match details |
| 2 | Felipe Etcheverry Cavanna | Jaguares XV | 02-04-2022 | Match details |
| 2 | Felipe Etcheverry Cavanna | Olimpia Lions | 04-05-2022 | Match details |
| 2 | Felipe Etcheverry Cavanna | Jaguares XV | 11-05-2022 | Match details |
| 1 | Felipe Etcheverry Cavanna | Cafeteros Pro | 30-04-2022 | Match details |
| 1 | Federico Favaro | Selknam | 16-05-2022 | Match details |
