| Penalties | Players | Club | VS Club | Date | |
|---|---|---|---|---|---|
| 3 |  Callum Sheedy | Bristol Bears | Harlequins | 19-06-2021 | Match details |
| 3 |  Robert du Preez | Sale Sharks | Exeter Chiefs | 19-06-2021 | Match details |
| 3 |  Joe Simmonds | Exeter Chiefs | Sale Sharks | 19-06-2021 | Match details |
| 1 | Joe Simmonds | Exeter Chiefs | Harlequins | 26-06-2021 | Match details |
