| A(D) | Club | VS | MD | |
|---|---|---|---|---|
| 30(68) | Begles-Bordeaux | La Rochelle | 09-Apr-2022 | Match Details |
| 29(181) | Scarlets | Begles-Bordeaux | 16-Jan-2022 | Match Details |
| 29(99) | Munster | Castres | 14-Jan-2022 | Match Details |
| 29(99) | Castres | Munster | 14-Jan-2022 | Match Details |
| 29(11) | La Rochelle | Montpellier | 07-May-2022 | Match Details |
| 29(350) | Clermont Auvergne | Leicester Tigers | 10-Apr-2022 | Match Details |
| 29(333) | Racing CF | Northampton Saints | 10-Dec-2021 | Match Details |
| 29(305) | Exeter Chiefs | Munster | 09-Apr-2022 | Match Details |
| 29(272) | Connacht | Leinster | 08-Apr-2022 | Match Details |
| 29(267) | London Wasps | Munster | 23-Jan-2022 | Match Details |
| 29(248) | Montpellier | La Rochelle | 07-May-2022 | Match Details |
| 29(202) | Leinster | Connacht | 08-Apr-2022 | Match Details |
| 28(158) | Ulster | Northampton Saints | 17-Dec-2021 | Match Details |
| 28(149) | Cardiff Blues | Harlequins | 14-Jan-2022 | Match Details |
| 28(25) | Leicester Tigers | Connacht | 15-Jan-2022 | Match Details |
| 28(314) | Sale Sharks | Racing CF | 08-May-2022 | Match Details |
| 28(240) | Northampton Saints | Ulster | 16-Jan-2022 | Match Details |
| 28(195) | Bristol Bears | Scarlets | 22-Jan-2022 | Match Details |
| 27(69) | Stade Francais | Connacht | 23-Jan-2022 | Match Details |
| 27(65) | Toulouse | Leinster | 14-May-2022 | Match Details |
| 27(25) | Bath | La Rochelle | 15-Jan-2022 | Match Details |
| 27(319) | Harlequins | Montpellier | 10-Apr-2022 | Match Details |
| 27(256) | Ospreys | Sale Sharks | 23-Jan-2022 | Match Details |
| 27(204) | Glasgow Warriors | La Rochelle | 22-Jan-2022 | Match Details |
MD = Match date,
A(D) = Age(days).