| Points | Players | VS Club | Date | |
|---|---|---|---|---|
| 13 | John Cooney | Harlequins | 04-04-2021 | Match details |
| 13 | John Cooney | Northampton Saints | 10-04-2021 | Match details |
| 10 | Robert Herring | Harlequins | 04-04-2021 | Match details |
| 10 | Sean Reidy | Harlequins | 04-04-2021 | Match details |
| 7 | John Cooney | Leicester Tigers | 30-04-2021 | Match details |
| 5 | Stuart McCloskey | Harlequins | 04-04-2021 | Match details |
| 5 | Michael Lowry | Harlequins | 04-04-2021 | Match details |
| 5 | Billy Burns | Harlequins | 04-04-2021 | Match details |
| 5 | Alby Mathewson | Harlequins | 04-04-2021 | Match details |
| 5 | Robert Herring | Northampton Saints | 10-04-2021 | Match details |
| 5 | Martin Moore | Northampton Saints | 10-04-2021 | Match details |
| 5 | Jacob Stockdale | Northampton Saints | 10-04-2021 | Match details |
| 5 | Iain Henderson | Leicester Tigers | 30-04-2021 | Match details |
| 5 | Billy Burns | Leicester Tigers | 30-04-2021 | Match details |
| 5 | Nick Timoney | Leicester Tigers | 30-04-2021 | Match details |
| 4 | Ian Madigan | Harlequins | 04-04-2021 | Match details |
| 2 | Michael Lowry | Leicester Tigers | 30-04-2021 | Match details |
