| Penalties | Players | VS Club | Date | |
|---|---|---|---|---|
| 3 | Julian Hernandez | Corinthians | 26-03-2022 | Match details |
| 2 | Nicolas Roger Farias | Olimpia Lions | 04-04-2021 | Match details |
| 2 | Tomas Garcia | Selknam | 11-04-2021 | Match details |
| 2 | Julian Hernandez | Selknam | 02-04-2022 | Match details |
| 2 | Eliseo Morales | Penarol | 21-05-2022 | Match details |
| 2 | Eliseo Morales | Olimpia Lions | 09-04-2022 | Match details |
| 2 | Eliseo Morales | Olimpia Lions | 15-05-2022 | Match details |
| 1 | Nicolas Roger Farias | Penarol | 25-03-2021 | Match details |
| 1 | Nicolas Roger Farias | Penarol | 21-04-2021 | Match details |
| 1 | Gonzalo Garcia | Penarol | 21-04-2021 | Match details |
| 1 | Franco Giudice | Selknam | 02-04-2022 | Match details |
| 1 | Eliseo Morales | Corinthians | 04-05-2022 | Match details |
| 1 | Julian Hernandez | Selknam | 10-05-2022 | Match details |
