| Points | Club | VS Club | Date | |
|---|---|---|---|---|
| 68 | London Welsh | Moseley | 16-10-2010 | Match details |
| 61 | Cornish Pirates | Birmingham Solihull | 15-12-2010 | Match details |
| 53 | Bedford Blues | Esher | 20-11-2010 | Match details |
| 48 | Worcester Warriors | Birmingham Solihull | 28-08-2010 | Match details |
| 46 | Nottingham | Birmingham Solihull | 12-11-2010 | Match details |
| 46 | Doncaster Knights | Nottingham | 02-10-2010 | Match details |
| 42 | Moseley | Birmingham Solihull | 29-01-2011 | Match details |
| 42 | Esher | Doncaster Knights | 12-02-2011 | Match details |
| 38 | Birmingham Solihull | Esher | 10-10-2010 | Match details |
| 37 | Rotherham Titans | Nottingham | 18-09-2010 | Match details |
| 36 | Plymouth Albion | Moseley | 30-10-2010 | Match details |
| 36 | Bristol Bears | Moseley | 28-11-2010 | Match details |
